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Side effects can temporarily worsen after Wegovy dose increases, but this does not happen for everyone

Suspected adverse reactions to any medicine, including unlicensed products, should be reported to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk or through the Yellow Card app

However, its successful application will require further elucidation of TREM biology in humans, regarding the cell-type specificity of TREM expression (e.g., in astrocytes, oligodendrocytes, and neurons), species differences between humans and mice, immature metabolic and mitochondrial features of in vitro culture (e.g., BV and iPSC-derived cells), early-onset or late-onset, and the temporal dynamics of disease progression with senescence

Therefore, practitioners should exercise caution when considering combination approaches, particularly for patients with existing cardiovascular risk factors

I just think that because the science is so new and because again, access to the medications is so limited, I just feel like this hasnt really broken out in the open in a way that the wider public knows about it and can celebrate it

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